BENNETT LAB PUBLICATIONS
Selected Publications and Reviews (2015 - present)

Yi, J.S., Perla, S. and Bennett, A.M. (2022) An assessment of the therapeutic landscape for the treatment of heart disease in the RASopathies, Cardiovascular Drugs Ther., DOI: 10.1007/s10557-022-07324-0.

 

Yi, J.S., Perla, S., Mizuno, K., Vinks, A., A. and Bennett, A.M. (2021) Low-dose dasatinib ameliorates hypertrophic cardiomyopathy in PTPN11-associated Noonan syndrome with multiple lentigines, Cardiovascular Drugs Ther., DOI: 10.1007/s10557-021-07169-z.

 

An allosteric site on MKP5 reveals a strategy for small molecule inhibition (2020) Gannam, Z.T.K., Min, K., Shillingford, S.R., Zhang, L., Herrington, J., Abriola, L., Gareiss, P.C., Pantouris, G., Tzouvelekis, A., Kaminski, N., Zhang, X., Yu, J., Jamali, H., Ellman, J.A., Lolis, E., Anderson, K.S., and Bennett, A.M., Science Signaling, 13(646).

 

Yi, J.S., Zhang, Perla, S., Enyenihi. and Bennett, A.M. (2020) Tyrosyl phosphorylation of PZR promotes hypertrophic cardiomyopathy in PTPN11-associated Noonan syndrome with multiple lentigines, J. Clin. Invest. Insight., 5(15):e137753.

 

Bennett, A.M. and Lawan, A. (2020) Improving Obesity and Insulin Resistance by Targeting Skeletal Muscle MKP-1, J. Cell Signal. 1(4): 160-168.

 

Xylourgidis, N., Kisuk, M., Ahangari, F., Yu, G., Herazo-Maya, J., Karampitsakos, J., Aidinis, V., Binzenhöfer, L., Bennett, A.M., Kaminski, N. and Tzouvelekis, A. (2019) Role for MKP-5 in the development of idiopathic pulmonary fibrosis, American Journal of Physiology-Lung Cellular and Molecular Physiology. 2019;317(5):L678-L689.

 

Lawan, A., Min, K., Canfran-Duque, A., Jurczak, M., Camporez, J. P. G., Nie, Y., Gavin, T.P., Shulman, G.I., Fernández-Hernando, C. and Bennett, A.M. (2018) Skeletal muscle-specific deletion of MKP-1 reveals a p38 MAPK/JNK/Akt signaling node that regulates obesity-induced insulin resistance, Diabetes, 67: 624-635.

 

Lawan, A. and Bennett, A.M. (2017) Mitogen-Activated Protein Kinase Regulation in Hepatic Metabolism, Trends in Endocrinology and Metabolism, Vol. 28, No. 12

 

Lee, H., Min, K., Yi, J.S., Shi, H., and Bennett, A.M. (2017) A phosphoproteomic screen identifies a guanine-nucleotide exchange factor for Rab3A as a MAP kinase phosphatase-5-regulated MAP kinase target in IL-6 secretion and myogenesis, J. Biol. Chem., jbc.M116.769208. doi: 10.1074/jbc.M116.769208.

 

Yi, J.S., Huang, Y., Kwaczala, A., Kuo, I., Ehrlich, B.E., Campbell, S., Giordano, F. and Bennett, A.M. (2016) Low-dose dasatinib selectively rescues cardiac function in a Ptpn11 mutant mouse model of Noonan syndrome, J. Clin. Invest. Insight;1(20):e90220.

 

Lawan, A., Zhang, L., Min, K., Gatzke, F., Jurczak, M.J., Al-Mutairi, M., Richter, P., Camporez, G., JP, Couvillon, A., Roth Flach, R. J., Shulman, G. I., and Bennett, A. M. (2015) Hepatic MAP kinase phosphatase-1 Selectively Regulates Glucose Metabolism and Energy Homeostasis, Mol. Cell. Biol., 35: 26-40.